Publications
Design, synthesis, in silico studies and in vitro evaluation of isatin-pyridine oximes hybrids as novel acetylcholinesterase reactivators
DAS Kitagawa, RB Rodrigues, TN Silva
Journal of Enzyme Inhibition and Medicinal Chemistry, Volume 36, Pages 1369-1376, 2021 - Issue 1
Extraction of Furfural and Furfural/5-Hydroxymethylfurfural from Mixed Lignocellulosic Biomass-Derived Feedstocks Zhaoxing Wang, Souryadeep Bhattacharyya, and Dionisios G. Vlachos ACS Sustainable Chem. Eng. 2021, 9, 22, 7489–7498
Reactions under increased pressure: The reactivity of functionally substituted 3-oxo-2-arylhydrazones toward active methylene reagents in Q-tube Douaa Salman AlMarzouq European Journal of Chemistry 12 (2) (2021) 154-158
Oxidative coupling of 2-methyl furoate: A scalable synthesis of dimethyl 2, 2'-bifuran-5, 5'-dicarboxylate M Ye, MJ Kuo, RF Lobo Applied Catalysis A: General, 2021 - Elsevier
Selective Synthesis of 4, 4′-Dimethylbiphenyl from 2-Methylfuran Hong Je Cho, Mi Jen Kuo, Mingchun Ye, Yannick Kurz, Yong Yuan, and Raul F. Lobo ACS Sustainable Chem. Eng. 2021, 9, 8, 3316–3323
Palladium-Catalyzed Q-Tube-Assisted Protocol for Synthesizing Diaza-dibenzo[a,e]azulene and Diaza-benzo[a]fluorene Derivatives via O2 Acid-Promoted Cross-Dehydrogenative Coupling Hamada Mohamed Ibrahim* and Haider Behbehani* J. Org. Chem. 2020, 85, 23, 15368–15381
High pressure assisted synthetic approach for novel 6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-b]pyridine and 5,6-dihydrobenzo[h]quinoline derivatives and their assessment as anticancer agents Haider Behbehani, Fatemah A. Aryan, Kamal M. Dawood & Hamada Mohamed Ibrahim Scientific Reports volume 10, Article number: 21691 (2020)
Reactions under Pressure: Synthesis of Functionally Substituted Arylhydrazonal Derivatives as Precursors of Novel Pyridazines and Nicotinates K. M. Al Zaydi, M. A. Al-Johani, N. F. Alqahtani, S. M. Mousally & N. Hilmy Elnagdi Russian Journal of General Chemistry volume 90, pages710–719 (2020)
The first Q-Tube based high-pressure synthesis of anti-cancer active thiazolo[4,5-c]pyridazines via the [4 + 2] cyclocondensation of 3-oxo-2-arylhydrazonopropanals with 4-thiazolidinones HM Ibrahim, H Behbehani Scientific reports, 2020 - https://www.nature.com/articles/s41598-020-63453-2
Glycerol and Q-Tubes: Green Catalyst and Technique for Synthesis of Polyfunctionally Substituted Heteroaromatics and Anilines DS AlMarzouq, NMH Elnagdi Molecules, 2019 - mdpi.com
One-Pot Synthesis of NEMP, a VX Surrogate, and Reactivation of NEMP-Inhibited Electrophorus Eel Acetylcholinesterase by Current Antidotes SFA Cavalcante, DAS Kitagawa J. Braz. Chem. Soc. 30 (5) • May 2019
Q-Tube assisted MCRs for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones Luca Sancineto, Bonifacio Monti, Orsola Merlino, Ornelio Rosati, and Claudio Santib Arkivoc 2018, part iii, 270-278
Organic Reactions under High Pressure: Efficient Multicomponent Synthesis of Novel Tricyclic Pyridazinonaphthyridine Derivatives under High Pressure Moustafa, Moustafa S.; Al-Mousawi, Saleh M. Current Organic Chemistry, Volume 22, Number 3, January 2018, pp. 268-275(8)
First multicomponent reaction exploiting glycerol carbonate synthesis P Costanzo, C Calandruccio, ML Di Gioia… Journal of Cleaner Production, Volme 202, Page 504-509, 2018 - Elsevier
Oxidation of aromatic oxygenates for the production of terephthalic acid Konstantinos A.Goulas, Mika Shiramizu, James R.Lattner, Basudeb Saha, Dionisios G.Vlachos Applied Catalysis A: General Volume 552, 25 February 2018, Pages 98-104
The Q-tube System, A Nonconventional Technology for Green Chemistry Practitioners Nacca, Francesca G.; Merlino, Orsola; Mangiavacchi, Francesca; Krasowska, Dorota; Santi, Claudio; Sancineto, Luca Current Green Chemistry, Volume 4, Number 2, August 2017, pp. 58-66(9)
Mechanism and kinetics of 1-dodecanol etherification over tungstated zirconia Julie Rorrer, Ying He, F. Dean Toste, Alexis T.Bell Journal of Catalysis, Volume 354, October 2017, Pages 13-23
Multi Component Reactions under Increased Pressure: On the Mechanism of Formation of Pyridazino[5,4,3-de][1,6]naphthyridine Derivatives by the Reaction of Malononitrile, Aldehydes and 2-Oxoglyoxalarylhydrazones in Q-Tubes Majdah A. AL-Johani, Khadijah M. Al-Zaydi, Sameera M. Mousally, Norah F. Alqahtani, Noha Hilmy Elnagdi and Mohamed H. Elnagdi Molecules 2017, 22(12), 2114
Hydroxyl Radicals via Collision-Induced Dissociation of Trimethylammonium Benzyl Alcohols Moore, Peter W., Hooker, Jordan P., Zavra, Athanasios, Khairallah, George N., Krenske, Elizabeth H., Bernhardt, Paul V., Quach, Gina, Moore, Evan G., O’Hair, Richard A. J. and William, Craig M. Australian Journal of Chemistry, 70 4: 397-406
Methods for producing fuels, gasoline additives, and lubricants Eric SACIA, Anbarasan PAZHAMALAI, Balakrishnan MADHESAN, Sanil Sreekumar,F. Dean Toste, Amit A. Gokhale, Martin E. Carrera, Alexis T. Bell, Gorkem GUNBAS US Patent 9738617B2
Integrated catalytic sequences for catalytic upgrading of bio-derived carboxylic acids to fuels, lubricants and chemical feedstocks Sankaranarayanapillai Shylesh, Amit A. Gokhale, Keyang Sun, Adam M. Grippo, Deepak Jadhav, Alice Yeh, Christopher R. Ho and Alexis T. Bell Sustainable Energy Fuels, 2017, 1, 1805-1809
INCORPORATION OF INDENO[2,1-c]FLUORENES INTO POLYMERS VIA NUCLEOPHILIC AROMATIC SUBSTITUTION NATHANIEL BRACKETT https://etd.ohiolink.edu/!etd.send_file?accession=wright1503673136761061&disposition=inline
THE SYNTHESIS AND CHARACTERIZATION OF DOUBLE AND TRIPLE TETHERED INDENO[2.1-c]FLUORENDIONES DANIEL K. GREENE https://etd.ohiolink.edu/!etd.send_file?accession=wright1513941221837164&disposition=inline
1H-Indole-3-carboxaldehyde: Synthesis and Reactions Eslam El-Sawy; Heba Abo-Salem; Adel Mandour Egyptian Journal of Chemistry, Article 1, Volume 60, Issue 5, September and October 2017, Page 723-751
Demulsification of Water-in-Heavy Crude Oil Emulsion using Amphiphilic Ammonium Salts as Demulsifiers Juan de la Cruz ClavelJuan C. NavarroRafael Martínez-Palou Tenside Surfactants Detergents: Vol. 54, No. 4, pp. 361-364.
Method to convert fermentation mixture into fuels F. Dean Toste, Pazhamalai Anbarasan, Joseph B. BINDER, Paul A. Willems, Douglas S. Clark, Zach Baer, Sanil Sreekumar, Harvey W. Blanch US Patent 9856427B2
New phenylazetidinecarboxylate or -carboxamide compounds Benaissa Boubia, Christine Massardier, Fabrice Guillier, Olivia Poupardin, Mireille Tallandier, Jerome Amaudrut, Michel Bondoux, Roelof Williem FEENSTRA, Maria Johana Petronella VAN DONGEN US20170066717A1
Heteroaryl amides as inhibitors of protein aggregation Wolfgang Wrasidlo, Emily M. Stocking US20180093979A1
Synergistic Effects in Bimetallic Palladium–Copper Catalysts Improve Selectivity in Oxygenate Coupling Reactions Konstantinos A. Goulas, Sanil Sreekumar, Yuying Song, Purnima Kharidehal, Gorkem Gunbas, Paul J. Dietrich, Gregory R. Johnson, Y. C. Wang, Adam M. Grippo, Lars C. Grabow, Amit A. Gokhale, and F. Dean Toste J. Am. Chem. Soc., 2016, 138 (21), pp 6805–6812
Nanostructured photoelectrochemical solar cell for nitrogen reduction using plasmon-enhanced black silicon Nature Communications 7, Article number: 11335 (2016) Muataz Ali, Fengling Zhou, Kun Chen, Christopher Kotzur, Changlong Xiao, Laure Bourgeois, Xinyi Zhang & Douglas R. MacFarlane
Use of a novel multicomponent reaction under high pressure for the efficient construction of a new pyridazino[5,4,3-de][1,6]naphthyridine tricyclic system Moustafa Sherief Moustafa, Saleh Mohammed Al-Mousawia and Mohamed Hilmy Elnagdib RSC Adv., 2016,6, 90840-90845
Multicomponent reactions in Q-Tubes: one-pot synthesis of benzo[c]chromen-6-one and phenanthridin-6(5H)-one derivatives in a four-component reaction Khadijah M. Alzaydia,, Nagat S. Abojabala, Mohamed Hilmy Elnagdib Tetrahedron Letters, Volume 57, Issue 32, 10 August 2016, Pages 3596–3599
Co-production of acetone and ethanol with molar ratio control enables production of improved gasoline or jet fuel blends Baer ZC, Bormann S, Sreekumar S, Grippo A, Toste FD, Blanch HW, Clark DS. Biotechnology and Bioengineering, 2016 Oct;113(10):2079-87
Pressure as effective green technology for synthesis of polyfunctionally substituted heteroaromatics: Synthesis of a variety of pyrazolo[1,5-a]pyrimidines Douaa Salman AlMarzouq, Omniya Sayed Zaky, Abdulaziz Abdulrazaq AlNajjar, Kamal Usef Sadek European Journal of Chemistry 2016, 7(3), 347-351
Feasibility of Using 2,3,3,3-Tetrafluoropropene (R1234yf) as a Solvent for Solid-Liquid Extraction of Biopharmaceuticals John Suberu, Peyman Yamin, Robert Cornell, Arya Sam, and Alexei Lapkin ACS Sustainable Chem. Eng. 2016, 4, 2559-2568
Extraction of Furfural and Furfural/5-Hydroxymethylfurfural from Mixed Lignocellulosic Biomass-Derived Feedstocks Zhaoxing Wang, Souryadeep Bhattacharyya, and Dionisios G. Vlachos ACS Sustainable Chem. Eng. 2021, 9, 22, 7489–7498
Reactions under increased pressure: The reactivity of functionally substituted 3-oxo-2-arylhydrazones toward active methylene reagents in Q-tube Douaa Salman AlMarzouq European Journal of Chemistry 12 (2) (2021) 154-158
Oxidative coupling of 2-methyl furoate: A scalable synthesis of dimethyl 2, 2'-bifuran-5, 5'-dicarboxylate M Ye, MJ Kuo, RF Lobo Applied Catalysis A: General, 2021 - Elsevier
Selective Synthesis of 4, 4′-Dimethylbiphenyl from 2-Methylfuran Hong Je Cho, Mi Jen Kuo, Mingchun Ye, Yannick Kurz, Yong Yuan, and Raul F. Lobo ACS Sustainable Chem. Eng. 2021, 9, 8, 3316–3323
Palladium-Catalyzed Q-Tube-Assisted Protocol for Synthesizing Diaza-dibenzo[a,e]azulene and Diaza-benzo[a]fluorene Derivatives via O2 Acid-Promoted Cross-Dehydrogenative Coupling Hamada Mohamed Ibrahim* and Haider Behbehani* J. Org. Chem. 2020, 85, 23, 15368–15381
High pressure assisted synthetic approach for novel 6,7-dihydro-5H-benzo[6,7]cyclohepta[1,2-b]pyridine and 5,6-dihydrobenzo[h]quinoline derivatives and their assessment as anticancer agents Haider Behbehani, Fatemah A. Aryan, Kamal M. Dawood & Hamada Mohamed Ibrahim Scientific Reports volume 10, Article number: 21691 (2020)
Reactions under Pressure: Synthesis of Functionally Substituted Arylhydrazonal Derivatives as Precursors of Novel Pyridazines and Nicotinates K. M. Al Zaydi, M. A. Al-Johani, N. F. Alqahtani, S. M. Mousally & N. Hilmy Elnagdi Russian Journal of General Chemistry volume 90, pages710–719 (2020)
The first Q-Tube based high-pressure synthesis of anti-cancer active thiazolo[4,5-c]pyridazines via the [4 + 2] cyclocondensation of 3-oxo-2-arylhydrazonopropanals with 4-thiazolidinones HM Ibrahim, H Behbehani Scientific reports, 2020 - https://www.nature.com/articles/s41598-020-63453-2
Glycerol and Q-Tubes: Green Catalyst and Technique for Synthesis of Polyfunctionally Substituted Heteroaromatics and Anilines DS AlMarzouq, NMH Elnagdi Molecules, 2019 - mdpi.com
One-Pot Synthesis of NEMP, a VX Surrogate, and Reactivation of NEMP-Inhibited Electrophorus Eel Acetylcholinesterase by Current Antidotes SFA Cavalcante, DAS Kitagawa J. Braz. Chem. Soc. 30 (5) • May 2019
Q-Tube assisted MCRs for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones Luca Sancineto, Bonifacio Monti, Orsola Merlino, Ornelio Rosati, and Claudio Santib Arkivoc 2018, part iii, 270-278
Organic Reactions under High Pressure: Efficient Multicomponent Synthesis of Novel Tricyclic Pyridazinonaphthyridine Derivatives under High Pressure Moustafa, Moustafa S.; Al-Mousawi, Saleh M. Current Organic Chemistry, Volume 22, Number 3, January 2018, pp. 268-275(8)
First multicomponent reaction exploiting glycerol carbonate synthesis P Costanzo, C Calandruccio, ML Di Gioia… Journal of Cleaner Production, Volme 202, Page 504-509, 2018 - Elsevier
Oxidation of aromatic oxygenates for the production of terephthalic acid Konstantinos A.Goulas, Mika Shiramizu, James R.Lattner, Basudeb Saha, Dionisios G.Vlachos Applied Catalysis A: General Volume 552, 25 February 2018, Pages 98-104
The Q-tube System, A Nonconventional Technology for Green Chemistry Practitioners Nacca, Francesca G.; Merlino, Orsola; Mangiavacchi, Francesca; Krasowska, Dorota; Santi, Claudio; Sancineto, Luca Current Green Chemistry, Volume 4, Number 2, August 2017, pp. 58-66(9)
Mechanism and kinetics of 1-dodecanol etherification over tungstated zirconia Julie Rorrer, Ying He, F. Dean Toste, Alexis T.Bell Journal of Catalysis, Volume 354, October 2017, Pages 13-23
Multi Component Reactions under Increased Pressure: On the Mechanism of Formation of Pyridazino[5,4,3-de][1,6]naphthyridine Derivatives by the Reaction of Malononitrile, Aldehydes and 2-Oxoglyoxalarylhydrazones in Q-Tubes Majdah A. AL-Johani, Khadijah M. Al-Zaydi, Sameera M. Mousally, Norah F. Alqahtani, Noha Hilmy Elnagdi and Mohamed H. Elnagdi Molecules 2017, 22(12), 2114
Hydroxyl Radicals via Collision-Induced Dissociation of Trimethylammonium Benzyl Alcohols Moore, Peter W., Hooker, Jordan P., Zavra, Athanasios, Khairallah, George N., Krenske, Elizabeth H., Bernhardt, Paul V., Quach, Gina, Moore, Evan G., O’Hair, Richard A. J. and William, Craig M. Australian Journal of Chemistry, 70 4: 397-406
Methods for producing fuels, gasoline additives, and lubricants Eric SACIA, Anbarasan PAZHAMALAI, Balakrishnan MADHESAN, Sanil Sreekumar,F. Dean Toste, Amit A. Gokhale, Martin E. Carrera, Alexis T. Bell, Gorkem GUNBAS US Patent 9738617B2
Integrated catalytic sequences for catalytic upgrading of bio-derived carboxylic acids to fuels, lubricants and chemical feedstocks Sankaranarayanapillai Shylesh, Amit A. Gokhale, Keyang Sun, Adam M. Grippo, Deepak Jadhav, Alice Yeh, Christopher R. Ho and Alexis T. Bell Sustainable Energy Fuels, 2017, 1, 1805-1809
INCORPORATION OF INDENO[2,1-c]FLUORENES INTO POLYMERS VIA NUCLEOPHILIC AROMATIC SUBSTITUTION NATHANIEL BRACKETT https://etd.ohiolink.edu/!etd.send_file?accession=wright1503673136761061&disposition=inline
THE SYNTHESIS AND CHARACTERIZATION OF DOUBLE AND TRIPLE TETHERED INDENO[2.1-c]FLUORENDIONES DANIEL K. GREENE https://etd.ohiolink.edu/!etd.send_file?accession=wright1513941221837164&disposition=inline
1H-Indole-3-carboxaldehyde: Synthesis and Reactions Eslam El-Sawy; Heba Abo-Salem; Adel Mandour Egyptian Journal of Chemistry, Article 1, Volume 60, Issue 5, September and October 2017, Page 723-751
Demulsification of Water-in-Heavy Crude Oil Emulsion using Amphiphilic Ammonium Salts as Demulsifiers Juan de la Cruz ClavelJuan C. NavarroRafael Martínez-Palou Tenside Surfactants Detergents: Vol. 54, No. 4, pp. 361-364.
Method to convert fermentation mixture into fuels F. Dean Toste, Pazhamalai Anbarasan, Joseph B. BINDER, Paul A. Willems, Douglas S. Clark, Zach Baer, Sanil Sreekumar, Harvey W. Blanch US Patent 9856427B2
New phenylazetidinecarboxylate or -carboxamide compounds Benaissa Boubia, Christine Massardier, Fabrice Guillier, Olivia Poupardin, Mireille Tallandier, Jerome Amaudrut, Michel Bondoux, Roelof Williem FEENSTRA, Maria Johana Petronella VAN DONGEN US20170066717A1
Heteroaryl amides as inhibitors of protein aggregation Wolfgang Wrasidlo, Emily M. Stocking US20180093979A1
Synergistic Effects in Bimetallic Palladium–Copper Catalysts Improve Selectivity in Oxygenate Coupling Reactions Konstantinos A. Goulas, Sanil Sreekumar, Yuying Song, Purnima Kharidehal, Gorkem Gunbas, Paul J. Dietrich, Gregory R. Johnson, Y. C. Wang, Adam M. Grippo, Lars C. Grabow, Amit A. Gokhale, and F. Dean Toste J. Am. Chem. Soc., 2016, 138 (21), pp 6805–6812
Nanostructured photoelectrochemical solar cell for nitrogen reduction using plasmon-enhanced black silicon Nature Communications 7, Article number: 11335 (2016) Muataz Ali, Fengling Zhou, Kun Chen, Christopher Kotzur, Changlong Xiao, Laure Bourgeois, Xinyi Zhang & Douglas R. MacFarlane
Use of a novel multicomponent reaction under high pressure for the efficient construction of a new pyridazino[5,4,3-de][1,6]naphthyridine tricyclic system Moustafa Sherief Moustafa, Saleh Mohammed Al-Mousawia and Mohamed Hilmy Elnagdib RSC Adv., 2016,6, 90840-90845
Multicomponent reactions in Q-Tubes: one-pot synthesis of benzo[c]chromen-6-one and phenanthridin-6(5H)-one derivatives in a four-component reaction Khadijah M. Alzaydia,, Nagat S. Abojabala, Mohamed Hilmy Elnagdib Tetrahedron Letters, Volume 57, Issue 32, 10 August 2016, Pages 3596–3599
Co-production of acetone and ethanol with molar ratio control enables production of improved gasoline or jet fuel blends Baer ZC, Bormann S, Sreekumar S, Grippo A, Toste FD, Blanch HW, Clark DS. Biotechnology and Bioengineering, 2016 Oct;113(10):2079-87
Pressure as effective green technology for synthesis of polyfunctionally substituted heteroaromatics: Synthesis of a variety of pyrazolo[1,5-a]pyrimidines Douaa Salman AlMarzouq, Omniya Sayed Zaky, Abdulaziz Abdulrazaq AlNajjar, Kamal Usef Sadek European Journal of Chemistry 2016, 7(3), 347-351
Feasibility of Using 2,3,3,3-Tetrafluoropropene (R1234yf) as a Solvent for Solid-Liquid Extraction of Biopharmaceuticals John Suberu, Peyman Yamin, Robert Cornell, Arya Sam, and Alexei Lapkin ACS Sustainable Chem. Eng. 2016, 4, 2559-2568